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搜索结果:找到“Tomy Martin”相关结果3条
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  • 【期刊】 嗜酸性粒细胞增多综合征1例

    刊名:临床皮肤科杂志 作者:Tomy Martin ; 李惠 ; 陈爱军 关键词:嗜酸性粒细胞增多综合征 机构:重庆医科大学附属第一医院皮肤性病科 ; 重庆医科大学附属第一医院皮肤性病科 ; 重庆医科大学附属第一医院皮肤性病科 ; 重庆医科大学附属第一医院皮肤性病科 ; 重庆400016印度尼西亚籍研究生 年份:2008
    摘要:患者男,63岁。因全身红斑、丘疹伴瘙痒5年,加重1个月,于2007年1月10日入院。患者5年前无明显诱因腹部出现红斑及米粒大丘疹,伴剧烈瘙痒,影响睡眠。患者曾自服中药(具
  • 【期刊】 重症药疹85例临床分析

    刊名:中国皮肤性病学杂志 作者:申卉 ; Tomy Martin ; 李惠 关键词:重症药疹 ; 回顾性分析 ; 致敏药物 机构:重庆医科大学附属第一医院皮肤科 ; 重庆医科大学附属第一医院皮肤科 年份:2015
    摘要:目的探讨重症药疹的临床特点及防治措施。方法对本科2002年8月-2013年11月诊治的重症药疹患者的临床资料进行回顾性分析。结果排名前三位的致敏药物分别为抗生素、抗癫痫药和解热镇痛药,最常见用药原因为感染。中成药引起的药疹内脏损害相对较轻。85例患者中,治愈61例,好转23例,1例死于肺部感染及呼吸衰竭。结论重症药疹是皮肤科危重病种,早期予以糖皮质激素联合免疫球蛋白效果较好,同时应加强对症及支持治疗。
  • 【期刊】 Severe cutaneous adverse drug reactions:a review on epidemiology,etiology,clinical manifestation and pathogenesis

    刊名:中华医学杂志(英文版) 作者:Tomy Martin ; LI Hui 关键词:severe cutaneous adverse drug eruptions ; drug hypersensitivity syndrome ; exfoliative dermatitis ; toxic epidermal necrolysis ; Steven Johnson syndrome 机构:First ; First ; Affiliated ; Hospital ; Chongqing ; Medical ; University ; Dermatology ; Venerology ; Department ; Chongqing ; China 年份:2008
    摘要:Purpose To review the current progress in epidemiology, etiology, clinical manifestation, and pathophysiology of severe cutaneous adverse drug reactions(SCADRs). Data sources Data were acquired by using Blackwell-Synergy, PubMed, original articles published in the main Chinese journals and related medical textbooks materials. Study-selection and date extraction Throughout the literature review 49 articles were selected. Results SCADRs cases are rare, however, the implication is life threatening with significant mortatity rates. Epidemiology studies have shown various incidences from different regions, gender, age, race and concurrent illness. There are typical signs and symptoms for each type of SCADRs, but this is not always so. Drugs associated with inducing SCADRs are anticonvulsants, antibiotics, NSAIDs and antirheumatic drugs. In some countries, especially in Asia, traditional drugs are offen the cause of SCADRs. Genetic polymorphisms and viral infections are predisposition factors of SCADRs. Patients with certain genetic alleles and underlying diseases are vulnerable to SCADRs. The exact pathogenesis of SCADRs is not well defined. Nonetheless, recent study showed that reactive metabolites and immunological processes have a significant role in SCADRs. Conclusions The different SCADRs reactions are attributed by different intrinsic factors, such as genetic polymorphisms, gender, age and race as well as extrinsic factors, such as underlying diseases. Different regions and culprit drugs also play a role in the various types of SCADRs.